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The Tennessee Junior Science and Humanities Symposium is administered by the University of Tennessee and is based in the Office of Research and Engagement. In addition to the Office of Research and Engagement, other supporting sponsors include the College of Arts and Sciences, College of Education, Health, and Human Sciences, the Tickle College of Engineering, UT-ORNL Science Alliance, and UT-Battelle, the management contractor of the Oak Ridge National Laboratory on behalf of the US Department of Energy.

The TJSHS sponsors the attendance and participation of selected statewide high school science students (grades 9–12). Basic funding for the TJSHS is provided by a grant from the National Science Teaching Association with supplementary funding provided by supporting sponsors.